Bi-Phasic Effect of Equol on Adipocyte Differentiation of MC3T3-L1 Cells

Yoriko NISHIDE; Yuko TOUSEN; Masaki INADA; Chisato MIYAURA; Yoshiko ISHIMI

doi:10.1271/bbb.120677

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Bi-Phasic Effect of Equol on Adipocyte Differentiation of MC3T3-L1 Cells

Yoriko NISHIDE, Yuko TOUSEN, Masaki INADA, Chisato MIYAURA, Yoshiko ISHIMI

著者情報

キーワード: isoflavone, equol, MC3T3-L1, adipogenesis

ジャーナルフリー早期公開

論文ID: 120677

DOI https://doi.org/10.1271/bbb.120677

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013) , No. 1 p.201

詳細

抄録

We investigated the effects of equol on adipogenesis by measuring lipid accumulation and analyzing the change in adipocyte-related gene expression in MC3T3-L1 cells. Treatment with 10 µM equol tended to increase adipocyte-related gene expression, whereas 100 µM equol reduced lipid accumulation and suppressed the expression of these genes and proteins. Our results suggest that equol regulated adipogenesis in a bi-phasic fashion.

責任著者(Corresponding author)

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