Department of Food Function and Labeling, National Institute of Health and Nutrition Cooperative Major in Advanced Health Science, Tokyo University of Agriculture and Technology
Yuko TOUSEN
Department of Food Function and Labeling, National Institute of Health and Nutrition
Masaki INADA
Cooperative Major in Advanced Health Science, Tokyo University of Agriculture and Technology
Chisato MIYAURA
Cooperative Major in Advanced Health Science, Tokyo University of Agriculture and Technology
Yoshiko ISHIMI
Department of Food Function and Labeling, National Institute of Health and Nutrition
We investigated the effects of equol on adipogenesis by measuring lipid accumulation and analyzing the change in adipocyte-related gene expression in MC3T3-L1 cells. Treatment with 10 µM equol tended to increase adipocyte-related gene expression, whereas 100 µM equol reduced lipid accumulation and suppressed the expression of these genes and proteins. Our results suggest that equol regulated adipogenesis in a bi-phasic fashion.
