Pou2f3/Skn-1a Is Necessary for the Generation or Differentiation of Solitary Chemosensory Cells in the Anterior Nasal Cavity

Makoto OHMOTO; Tatsuya YAMAGUCHI; Junpei YAMASHITA; Alexander A BACHMANOV; Junji HIROTA; Ichiro MATSUMOTO

doi:10.1271/bbb.130454

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Pou2f3/Skn-1a Is Necessary for the Generation or Differentiation of Solitary Chemosensory Cells in the Anterior Nasal Cavity

Makoto OHMOTO, Tatsuya YAMAGUCHI, Junpei YAMASHITA, Alexander A BACHMANOV, Junji HIROTA, Ichiro MATSUMOTO

著者情報

キーワード: transcription factor, Pou2f3, solitary chemosensory cell, differentiation, taste cell

ジャーナルフリー早期公開

論文ID: 130454

DOI https://doi.org/10.1271/bbb.130454

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013) , No. 10 p.2154-2156

詳細

抄録

Solitary chemosensory cells in the non-neuronal epithelium of the anterior nasal cavity have bitter taste cell-like molecular characteristics and are involved in the detection of noxious substances. Here, we demonstrate that Pou2f3/Skn-1a, which is necessary for generation of sweet, umami, and bitter taste cells, is also necessary for the generation or differentiation of solitary chemosensory cells.

責任著者(Corresponding author)

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