Partition Coefficients of Polyphenols for Phosphatidylcholine Investigated by HPLC with an Immobilized Artificial Membrane Column

Yoshinori UEKUSA; Yuko TAKESHITA; Takeshi ISHII; Tsutomu NAKAYAMA

doi:10.1271/bbb.80435

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Partition Coefficients of Polyphenols for Phosphatidylcholine Investigated by HPLC with an Immobilized Artificial Membrane Column

Yoshinori UEKUSA, Yuko TAKESHITA, Takeshi ISHII, Tsutomu NAKAYAMA

著者情報

キーワード: polyphenol, immobilized artificial membrane (IAM), HPLC, lipid membranes, IAM partition coefficient (K_IAM)

ジャーナルフリー早期公開

論文ID: 80435

DOI https://doi.org/10.1271/bbb.80435

この記事には本公開記事があります。

The final version of this article is now available: Vol. 72 (2008) , No. 12 p.3289

詳細

抄録

The biological activity of polyphenols in vitro reflects their affinity for cell membranes and the amount of cellular incorporation. The interaction of polyphenols with phosphatidylcholine was investigated by HPLC with an immobilized artificial membrane (IAM) column. The IAM partition coefficients (K_IAM) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes.

責任著者(Corresponding author)

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