Effects of Psilocybe argentipes on Marble-Burying Behavior in Mice

Yoshihiro MATSUSHIMA; Osamu SHIROTA; Ruri KIKURA-HANAJIRI; Yukihiro GODA; Fumio EGUCHI

doi:10.1271/bbb.90095

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引用する場合も本公開記事を引用してください。

Effects of Psilocybe argentipes on Marble-Burying Behavior in Mice

Yoshihiro MATSUSHIMA, Osamu SHIROTA, Ruri KIKURA-HANAJIRI, Yukihiro GODA, Fumio EGUCHI

著者情報

キーワード: Psilocybe argentipes, hallucinogenic mushrooms, psilocybin, marble-burying behavior, obsessive-compulsive disorder

ジャーナルフリー早期公開

論文ID: 90095

DOI https://doi.org/10.1271/bbb.90095

この記事には本公開記事があります。

The final version of this article is now available: Vol. 73 (2009) , No. 8 p.1866

詳細

抄録

Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy.

責任著者(Corresponding author)

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