Effects of Flavangenol on Autonomic Nerve Activities and Dietary Body Weight Gain in Rats

Mamoru TANIDA; Nobuo TSURUOKA; Jiao, SHEN; Yuko HORII; Yoshinori BEPPU; Yoshinobu KISO; Katsuya NAGAI

doi:10.1271/bbb.90196

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Effects of Flavangenol on Autonomic Nerve Activities and Dietary Body Weight Gain in Rats

Mamoru TANIDA, Nobuo TSURUOKA, Jiao, SHEN, Yuko HORII, Yoshinori BEPPU, Yoshinobu KISO, Katsuya NAGAI

著者情報

キーワード: gastric parasympathetic nerve, sympathetic nerve, brown adipose tissue, obesity, thermogenesis

ジャーナルフリー早期公開

論文ID: 90196

DOI https://doi.org/10.1271/bbb.90196

この記事には本公開記事があります。

The final version of this article is now available: Vol. 73 (2009) , No. 11 p.2374

詳細

抄録

In a previous report, evidence was presented that flavangenol supplementation has an anti-ischemic effects in rats. In the study presented here, we examined the autonomic effects of intraduodenal (ID) injection of flavangenol in urethane-anesthetized rats and found that it increased sympathetic nerve activity innervating brown adipose tissue (BAT-SNA) in a dose-dependent manner, while it suppressed gastric vagal nerve activity (GVNA). In addition, intra-oral (IO) injection of flavangenol elevated brown adipose tissue temperature (BAT-T). Furthermore, flavangenol drinking for 15 d reduced body weight gain in rats fed a high-fat diet. These results thus suggest that flavangenol supplementation exerts its reducing action on body weight through changes in autonomic neurotransmission.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）