Studies on the Organophosphorus Insecticides Part II.

Synthesis and Toxicity of Phosphoroates and Phosphorothioates Containing Phenylacrylate or Phenylacrylonitrile Radicals

Abstract

During an investigation of organophosphorus insectiside, the present author found that the reactions of O, O-dialkyl phosphorochloridate or O, O-dialkyl phosphorochloridothioates with sodium salts of β-keto-esters or nitriles give new phosphoroates or phosphorothioates containg Phenylacrylate or phenylacrylonitrile radicals, but do not give phosphonates.
The reactions of trialkylphosphites with α-halo-or α, α-dihalo-phenyl-β-keto-esters or nitrils also gave phosphoroates. Some phosphoroates prepared by this methods have high insecticidal activity.