抄録
The effect of overnight fasting on the fatty acid composition and structure of glycerolipids in rat liver and its microsomes was examined. Fasting caused alterations in the fatty acid composition of each glycerolipid in the different ways. Decreased percentage of linoleate and increased percentage of arachidonate were observed in phosphatidylcholine (PC) and phosphatidylethanolamine (PE). In contrast, linoleate was increased and oleate was decreased in triglyceride (TG). Increased percentage of tetraenoic PC species was dependent on the increase in stearoyl-arachidonyl species. In TG, palmitoyl-dilinolyl and more polyunsaturated species were increased markedly.
These results suggest that the metabolism of hepatic glycerolipids is completely modified in the fasting rats.
