1989 Volume 53 Issue 4 Pages 1025-1036
A variety of immunomodulators were synthesized by combining biologically active derivatives of 1-thio-muramoyl dipeptide with 4-O-phosphono-D-glucosamine derivatives related to bacterial lipid A, and using the (succinoylamino)undecanoyl group as a spacer. Their immunoadjuvant activities in guinea-pigs were examined.
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