THE EFFECT OF AGE AND ADRENALECTOMY ON THE D-AMINO ACID OXIDASE ACTIVITY OF RAT LEVER
1954 年 41 巻 4 号 p. 409-413
詳細
1954 年 41 巻 4 号 p. 409-413
1. The D-amino acid oxidase activity of the livers of newborn Wistar strain rats is about 15 per cent of the adult liver level. The rate of increase is slightly slower than that of succinoxidase but much faster than choline oxidase.
2. In normal rat liver the D-amino acid oxidase is approximately equally distributed between the mitochondrial and supernatant fractions with less than 10 per cent of the activity associated with the nuclear fraction.
3. In adrenalectomized rats the D-amino acid oxidase activity was reduced by about 20 per cent, and this loss occurred in the mitochondrial fraction.
4. Adrenalectomy caused no marked change in choline oxidase activity of rat liver, nor any alteration of its distribution pattern.
