2001 年 41 巻 2 号 p. 86-90
Inner-arm dynein subspecies c (dynein c) of Chlamydomonas flagella is the single-headed dynein which is capable of generating force on microtubules. We recently found that dynein c is a processive motor: a single molecule of dynein c is required to move a microtubule more than 1 μm. However, the duty ratio of dynein c, i.e. the proportion of strongly attached to total ATPase cycle, was estimated to be ca. 14%. This feature is distinct from that of kinesin which is known to be a two-headed processive motor with the higher duty ratio.