Faecalibacterium prausnitzii is not decreased in symptomatic uncomplicated diverticular disease of the colon

Antonio TURSI; Paola MASTROMARINO; Daniela CAPOBIANCO; Walter ELISEI; Giuseppe CAMPAGNA; Marcello PICCHIO; GianMarco GIORGETTI; Federica FABIOCCHI; Giovanni BRANDIMARTE

doi:10.12938/bmfh.2022-046

Letter to the editor

Faecalibacterium prausnitzii is not decreased in symptomatic uncomplicated diverticular disease of the colon

Antonio TURSI, Paola MASTROMARINO, Daniela CAPOBIANCO, Walter ELISEI, Giuseppe CAMPAGNA, Marcello PICCHIO, GianMarco GIORGETTI, Federica FABIOCCHI, Giovanni BRANDIMARTE

著者情報

Antonio TURSI
Territorial Gastroenterology Service, Azienda Sanitaria Locale, Barletta-Andria-Trani, Andria 76123, Italy
Department of Medical and Surgical Sciences, Catholic University, Rome, Italy
Paola MASTROMARINO
Department of Public Health and Infectious Diseases, Section of Microbiology, Sapienza University, Rome, Italy
Daniela CAPOBIANCO
Department of Public Health and Infectious Diseases, Section of Microbiology, Sapienza University, Rome, Italy
Walter ELISEI
Division of Gastroenterology, S. Camillo-Forlanini Hospital, Rome, Italy
Giuseppe CAMPAGNA
Department of Experimental Medicine, Sapienza University, Rome, Italy
Marcello PICCHIO
Division of Surgery, P. Colombo Hospital, ASL Roma 6, Velletri (Rome), Italy
GianMarco GIORGETTI
Digestive Endoscopy and Nutrition Unit, S. Eugenio Hospital, Rome, Italy
Federica FABIOCCHI
Digestive Endoscopy and Nutrition Unit, S. Eugenio Hospital, Rome, Italy
Giovanni BRANDIMARTE
Division of Internal Medicine and Gastroenterology, Cristo Re Hospital, Rome, Italy

キーワード: diverticular disease, fecal microbiota, Faecalibacterium prausnitzii

ジャーナルオープンアクセス

2023 年 42 巻 1 号 p. 1-2

DOI https://doi.org/10.12938/bmfh.2022-046

Browse “Advance online publication” version

詳細

抄録

In this letter, assessment of the amount of fecal Faecalibacterium prausnitzii in symptomatic uncomplicated diverticular disease (SUDD) is described. Among 44 consecutive patients, comprising 15 SUDD patients, 13 patients with asymptomatic diverticulosis (AD), and 16 healthy controls (HC), the fecal amount of Faecalibacterium prausnitzii was not found to be significantly different between HC, AD and SUDD subjects (p=0.871). Moreover, its count in the HC microbiota (−4.57 ± 2.15) was lower compared with those in the AD (−4.11 ± 1.03) and SUDD subjects (−4.03 ± 1.299). This behavior seems to be different from that occurring in inflammatory bowel disease (IBD) and similar to that of other mucin-degrading species in a SUDD setting.

責任著者(Corresponding author)

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