Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study

Motoi TAMURA; Sachiko HORI; Hiroyuki NAKAGAWA; Kazuhiro KATADA; Kazuhiro KAMADA; Kazuhiko UCHIYAMA; Osamu HANDA; Tomohisa TAKAGI; Yuji NAITO; Toshikazu YOSHIKAWA

doi:10.12938/bmfh.2014-019

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Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study

Motoi TAMURA, Sachiko HORI, Hiroyuki NAKAGAWA, Kazuhiro KATADA, Kazuhiro KAMADA, Kazuhiko UCHIYAMA, Osamu HANDA, Tomohisa TAKAGI, Yuji NAITO, Toshikazu YOSHIKAWA

著者情報

キーワード: daidzein, dihydrodaidzein, equol, microbiota

ジャーナルフリー早期公開

論文ID: 2014-019

DOI https://doi.org/10.12938/bmfh.2014-019

この記事には本公開記事があります。

The final version of this article is now available: Vol. 34 (2015), No. 3 pp. 59-65

詳細

抄録

To investigate the relationships among fecal isoflavone metabolism, dietary habit and Body Mass Index (BMI), 15 healthy men and 15 healthy women were recruited and provided stool samples for analysis of ex vivo anaerobic incubation of fecal suspension with daidzein. A negative correlation was observed between BMI and the dihydrodaidzein (DHD) production in men, and between BMI and the equol production in women. There was a positive correlation between intake of soluble dietary fiber and the DHD production in men. The results suggest that dietary habits and BMI are related to the metabolic activity of isoflavonoids by fecal intestinal microbiota.

責任著者(Corresponding author)

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