Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Notes
Inhibitory Activity of Lignan Components from the Flower Buds of Magnoliae fargesii on the Expression of Cell Adhesion Molecules
Kyung-Seop AHNKeun Young JUNGJung-Hee KIMSei Ryang OHHyeong-Kyu LEE
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2001 Volume 24 Issue 9 Pages 1085-1087

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Abstract

Inhibitory activity of lignans isolated from Magnoliae fargesii CHENG on cell adhesion molecules on the surface of THP-1 human monocytic cell lines were investigated. Among 16 lignan components tested, six displayed relatively potent inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1).

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© 2001 The Pharmaceutical Society of Japan
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