The Suppressive Effect of Mangiferin with Exercise on Blood Lipids in Type 2 Diabetes

Toshihiro MIURA; Naoki IWAMOTO; Motoshi KATO; Hiroyuki ICHIKI; Masayoshi KUBO; Yasuhiro KOMATSU; Torao ISHIDA; Minoru OKADA; Keiichiro TANIGAWA

doi:10.1248/bpb.24.1091

Notes

The Suppressive Effect of Mangiferin with Exercise on Blood Lipids in Type 2 Diabetes

Toshihiro MIURA, Naoki IWAMOTO, Motoshi KATO, Hiroyuki ICHIKI, Masayoshi KUBO, Yasuhiro KOMATSU, Torao ISHIDA, Minoru OKADA, Keiichiro TANIGAWA

Author information

Toshihiro MIURA
Department of Clinical Nutrition, Suzuka University of Medical Science
Naoki IWAMOTO
Department of Clinical Nutrition, Suzuka University of Medical Science
Motoshi KATO
Department of Clinical Nutrition, Suzuka University of Medical Science
Hiroyuki ICHIKI
Tsumura Central Research Laboratories, Tsumura and Co.
Masayoshi KUBO
Tsumura Central Research Laboratories, Tsumura and Co.
Yasuhiro KOMATSU
Tsumura Central Research Laboratories, Tsumura and Co.
Torao ISHIDA
Hi-tech Research Center, Suzuka University of Medical Science
Minoru OKADA
Tsumura Central Research Laboratories, Tsumura and Co.
Keiichiro TANIGAWA
Department of Clinical Nutrition, Suzuka University of Medical Science

Keywords: mangiferin, hypolipidemic effect, type 2 diabetes

JOURNAL FREE ACCESS

2001 Volume 24 Issue 9 Pages 1091-1092

DOI https://doi.org/10.1248/bpb.24.1091

Details

Abstract

The effect of mangiferin (MF) with exercise on bood lipids was studied in KK-A^y mice, an animal model of type 2 diabetes. MF (30 mg/kg) reduced the blood cholesterol (p<0.05) and triglyceride level (p<0.01) of KK-A^y mice with exercise 2 weeks after oral administration when compared with the control group. Diabetes also often has elevated lipid levels. Therefore, it may be that MF has beneficial effects on hyperlipidemia in type 2 diabetes.

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