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Biological and Pharmaceutical Bulletin
Vol. 29 (2006) No. 1 P 172-173




A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 μg/ml and the IC50 value was 50 μg/ml.

Copyright © 2006 The Pharmaceutical Society of Japan

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