Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
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Inhibition of Helicobacter pylori Motility by (+)-Syringaresinol from Unripe Japanese Apricot
Mitsuo MiyazawaHirotoshi UtsunomiyaKen-ichi InadaTomoki YamadaYoshiharu OkunoHarunari TanakaMasae Tatematsu
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2006 Volume 29 Issue 1 Pages 172-173

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Abstract

A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 μg/ml and the IC50 value was 50 μg/ml.

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© 2006 The Pharmaceutical Society of Japan
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