Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Notes
Protective Effect of Lutein on Ischemia-Reperfusion Injury in Rat Small Intestine
Wakako OguraShirou ItagakiToshimitsu KurokawaToshihiro NodaTakeshi HiranoSatoshi MizunoKen Iseki
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2006 年 29 巻 8 号 p. 1764-1766

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Lutein is a carotenoid and it has antioxidant effects. Lutein may have a protective effect on ischemia reperfusion (I/R) injury induced by free radical species. However, little is known about the protective effect of lutein on I/R injury in vivo. The present study was undertaken to clarify the protective effects of lutein on I/R injuries in the rat small intestine. Administration of lutein before intestinal I/R attenuated the damage to villi and deciduation of enterocytes and suppressed the increase in lipid peroxide.

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© 2006 The Pharmaceutical Society of Japan
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