2025 Volume 48 Issue 3 Pages 234-240
We examined whether the glucose levels and awareness of individuals without diabetes changed after using a sensor-based intermittently scanned continuous glucose monitoring (isCGM) system in their daily lives. Japanese individuals without a diabetes diagnosis wore the isCGM system while maintaining a normal lifestyle during the baseline period. A certified diabetes educator coached them on how to improve their lifestyle based on information from sensor data, food journals, and body composition. The participants subsequently consumed a specific diet, exercised for 2 months, and wore a new sensor after the intervention period. A total of 36 Japanese participants were eligible for analysis in this study. The time above range and the area under the curve did not change between before and after the intervention in overall participants. The visual analogue scale scores significantly increased from before to after the intervention in the overall participants. Stratified analysis was performed by dividing the participants into 18 control participants (glycated hemoglobin level <5.7%) and 18 participants with prediabetes (glycated hemoglobin level 5.7–6.4%). The time in range and the area under the curve significantly increased and decreased after the intervention in participants with prediabetes but not in control participants. The visual analogue scale scores significantly increased from before to after the intervention in both control and prediabetes groups individually. Lifestyle modification, along with the use of an isCGM system, is highly effective at preventing type 2 diabetes mellitus, potentially reducing the individual and public health burdens of diabetes, particularly for individuals with prediabetes.