Journal of Pharmacobio-Dynamics
Online ISSN : 1881-1353
Print ISSN : 0386-846X
ISSN-L : 0386-846X
A DECREASE IN ACETYLCHOLINE CONTENT OF THE RAT VAS DEFERENS AFTER SURGICAL DENERVATION
AKIRA SAITOYUTAKA KASUYA
著者情報
キーワード: reserpine
ジャーナル フリー

1979 年 2 巻 3 号 p. 190-191

詳細
抄録
Acetylcholine contents of the rat vasa deferentia were measured after surgical denervation, daily reserpine treatment or 6-hydroxydopamine pretreatment, all of which are known to cause a decrease in norepinephrine contents. Denervation and reserpine treatment are known to cause nonspecific supersensitivity to agonists. Denervation caused a decrease in acetylcholine content but reserpine and 6-hydroxydopamine failed. It is suggested that surgical denervation causes adrenergic and cholinergic denervation and that acetylcholine content per se is not causally related to the appearance of nonspecific supersensitivity.
著者関連情報
© The Pharmaceutical Society of Japan
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