Journal of Pharmacobio-Dynamics
Online ISSN : 1881-1353
Print ISSN : 0386-846X
ISSN-L : 0386-846X
OCCURRENCE OF LOOSELY BOUND MERCURY IN THE BLOOD OF GUINEA PIG TREATED WITH METHYLMERCURIC CHLORIDE
YUTAKA UDAYASUO NAKAZAWA
著者情報
キーワード: proteolipid
ジャーナル フリー

1979 年 2 巻 4 号 p. 245-250

詳細
抄録
Guinea pigs were given 203Hg-labeled methylmercuric chloride or mercuric chloride and then the distribution of mercury in the blood, brain and liver was investigated. The methylmercury in the blood and brain was extracted with a chloroform-methanol mixture. Most of the extractable mercury from the blood was detected in the proteolipid fraction by further fractionation. The mercury in the chloroform-methanol extract was also dialyzable against the same solvent. These findings suggest the occurrence of loosely bound mercury in the blood after administration of methylmercury.
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© The Pharmaceutical Society of Japan
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