Possible Antifertility Agents Belonging to Substituted Indoles

抄録

Of the 21 compounds evaluated for antiimplantation and abortifacient activities, compounds (A₁, A₂, A₄ and B₁) and compounds (C₁, C₂, D₁ and D₃) were found to exhibit 40% and 30% antimplantation activity, respectively, in female rats when given orally on days 1-5 postcoitum. The remaining 13 compounds were found to be inactive. All of the 21 compounds were also tested for the abortifacient activity, but all were found to be inactive.