ATOMIC FORCE MICROSCOPY OF DIMYRISTOYLPHOSPHATIDYLCHOLINE MEMBRANES

Yukio SATO; Zhansong CHEN; Takeo TAKAHASHI; Yasuo SUZUKI

doi:10.1248/bpb.17.1682

Yukio SATO, Zhansong CHEN, Takeo TAKAHASHI, Yasuo SUZUKI

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Keywords: atomic force microscope, dimyristoylphosphatidylcholine, Langmuir-Blodgett film, small unilamellar vesicle, lattice structure

JOURNAL FREE ACCESS

1994 Volume 17 Issue 12 Pages 1682-1685

DOI https://doi.org/10.1248/bpb.17.1682

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Abstract

We have observed the surface images of dimyristoylphosphatidylcholine (DMPC) monolayer and DMPC vesicles with an atomic force microscope (AFM). It was confirmed that the lattice structure of polar head groups of DMPC molecules in a Langmuir-Blodgett monolayer is similar to those of large unilamellar DMPC vesicles. AFM images of small unilamellar vesicles of DMPC showed larger lattice structures than those of the monolayer, reflecting differences of molecular packing in these membranes.

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