Anaphylactoid Shock Caused by 5% Human Serum Albumin Transfusion

抄録

A 38-year-old woman underwent bilateral adnexectomy and partial omentectomy procedures for diagnosed ovarian cancer, and developed anaphylactoid shock after administration of 5% human serum albumin(HSA). She had no history of drug or food allergic reactions, nor any previous blood transfusions. Immediately after 5% HSA transfusion, blood pressure dropped to 60/35 mmHg and heart rate increased to 100 bpm. On the basis of her clinical course, we concluded that albumin had induced anaphylactoid shock. Consequently, we discontinued the albumin product transfusion and administered epinephrine, after which the symptoms improved. The concentration of plasma tryptase was remarkably elevated to 64.1μg·l^－1 at 1 hour after the occurrence of symptoms.