抄録
Background The effect of physical training on insulin resistance (IR) in chronic heart failure (CHF) remains unclear. Methods and Results Fourteen patients with CHF performed physical training using a bicycle ergometer; 9 patients (64%) were hyperinsulinemic and insulin resistant (HOMA IR >1.97). Exercise tolerance increased (5.1±1.7 to 6.9±2.7 METs, p<0.05) and heart rate at rest decreased (82±15 to 72±6, p<0.05) in the IR group after physical training. Physical training also decreased the insulin level (15.1 ±5.6 to 9.8±2.6 μU/ml, p<0.05) and HOMA IR (3.7±1.4 to 2.3±0.6, p<0.05) in the IR group, but not in the 5 patients (36%) without IR or in 6 control patients. Conclusion Physical training can improve hyperinsulinemia and IR in patients with CHF. (Circ J 2006; 70: 864 - 867)
