Incidence of Premature Discontinuation of Antiplatelet Therapy After Sirolimus-Eluting Stent Implantation

Yo Iwata; Yoshio Kobayashi; Kenichi Fukushima; Hideki Kitahara; Tatsuhiko Asano; Naoki Ishio; Takashi Nakayama; Nakabumi Kuroda; Issei Komuro

doi:10.1253/circj.72.340

Rapid Communication

Incidence of Premature Discontinuation of Antiplatelet Therapy After Sirolimus-Eluting Stent Implantation

Yo Iwata, Yoshio Kobayashi, Kenichi Fukushima, Hideki Kitahara, Tatsuhiko Asano, Naoki Ishio, Takashi Nakayama, Nakabumi Kuroda, Issei Komuro

著者情報

キーワード: Antiplatelet therapy, Drug-eluting stent, Late stent thrombosis

ジャーナルフリー

2008 年 72 巻 2 号 p. 340-341

DOI https://doi.org/10.1253/circj.72.340

詳細

抄録

Background Antiplatelet therapy in patients with sirolimus-eluting stents (SES) may be stopped because of bleeding or an invasive procedure. Methods and Results In 254 patients with SES, the incidence of discontinuation of antiplatelet therapy and subsequent adverse cardiac events was evaluated. Follow-up was complete for 97.2% of the population and mean follow-up was 15.6±8.9 months. Discontinuation of antiplatelet therapy occurred for 46 patients (18.1%): 1 case of late stent thrombosis (2.2%) occurred 10 days after cessation of therapy because of pulmonary hemorrhage 7 months after SES deployment. Conclusion Discontinuation of antiplatelet therapy in patients with SES is not infrequent. (Circ J 2008; 72: 340 - 341)

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