Restored Cardiac Conditions and Left Ventricular Function After Parathyroidectomy in a Hemodialysis Patient Parathyroidectomy Improves Cardiac Fatty Acid Metabolism Assessed by <sup>123</sup>I-BMIPP

Mamoru Nanasato; Norihiko Goto; Satoshi Isobe; Kazumasa Unno; Haruo Hirayama; Tetsuhiko Sato; Susumu Matsuoka; Takaharu Nagasaka; Yoshihiro Tominaga; Kazuharu Uchida; Toyoaki Murohara

doi:10.1253/circj.CJ-08-0415

Case Reports

Restored Cardiac Conditions and Left Ventricular Function After Parathyroidectomy in a Hemodialysis Patient

Parathyroidectomy Improves Cardiac Fatty Acid Metabolism Assessed by ¹²³I-BMIPP

Mamoru Nanasato, Norihiko Goto, Satoshi Isobe, Kazumasa Unno, Haruo Hirayama, Tetsuhiko Sato, Susumu Matsuoka, Takaharu Nagasaka, Yoshihiro Tominaga, Kazuharu Uchida, Toyoaki Murohara

著者情報

キーワード: Hemodialysis, Left ventricular function, Parathyroidectomy, Scintigraphy

ジャーナルフリー

2009 年 73 巻 10 号 p. 1956-1960

DOI https://doi.org/10.1253/circj.CJ-08-0415

View "Advance Publication" version (January 27, 2009).

詳細

抄録

A 62 year-old female hemodialysis patient underwent parathyroidectomy to treat secondary hyperparathyroidism. On the preoperative assessment, the plasma levels of parathyroid hormone (PTH) and B-type natriuretic peptide (BNP) were elevated. Echocardiography showed reduced left ventricular (LV) contraction. Myocardial iodine-123-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid (¹²³I-BMIPP) scintigraphy showed moderately reduced tracer uptake in the postero-inferior area on single-photon emission computed tomography and decreased washout on the planar images. After parathyroidectomy, the plasma levels of PTH and BNP decreased, followed by improvement in LV contraction. Myocardial ¹²³I-BMIPP scintigraphy revealed that the washout on planar images had increased, which suggests that myocardial ¹²³I-BMIPP scintigraphy is useful for estimating the effect of parathyroidectomy on cardiac function. (Circ J 2009; 73: 1956-1960)

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