Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Cardiovascular Surgery
Long-Term Outcome of Aortic Root Remodeling for Patients With and Without Acute Aortic Dissection
Takashi KuniharaNiklas NeumannSteffen Daniel KriechbaumRyota NomuraHans-Joachim Schäfers
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2017 Volume 81 Issue 12 Pages 1824-1831

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Abstract

Background:Valve-preserving aortic surgery is increasingly used in acute aortic dissection type A (AADA). The object of this study was to compare the long-term results of aortic root remodeling (remodeling) for patients with and without AADA.

Methods and Results:Between October 1995 and December 2013, 776 patients underwent valve-preserving root replacement, of whom 59 patients with AADA (<2 weeks from onset, 56±16 years, 48 male) underwent remodeling (the remodeling-group); 7 patients had bicuspid anatomy (12%), 3 had Marfan syndrome (5%), and 1 had undergone previous cardiac surgery (2%). For this analysis the control group of patients who underwent remodeling for stable aneurysm (n=59) was generated using a propensity score matching. The long-term outcomes regarding survival and reoperation on the aortic valve were compared between the 2 groups. Pre- and intraoperative patients’ characteristics were comparable between groups. Early death was 7% in the AADA group and 3% in the control group (P=0.40). Actuarial survival at 10 years of the AADA group (72±6%) was insignificantly lower than that of the control group (83±5%) (P=0.16). Freedom from reoperation at 10 years was similar (AADA group: 98±2%, control group: 97±3%, P=0.99). Multivariable Cox’s proportional hazards model could not identify an independent predictor for late reoperation but advanced age for late death.

Conclusions:Long-term stability of remodeling was comparable between patients with and without AADA.

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© 2017 THE JAPANESE CIRCULATION SOCIETY
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