Evaluation of High-Sensitivity Cardiac Troponin T Levels in Japanese Patients Recently Recovered From Coronavirus Disease 2019

Satoshi Ide; Hiromasa Hayama; Yusuke Asai; Mari Terada; Hidetoshi Nomoto; Satoshi Kutsuna; Norio Ohmagari; Yukio Hiroi

doi:10.1253/circj.CJ-21-0219

Rapid Communications

Evaluation of High-Sensitivity Cardiac Troponin T Levels in Japanese Patients Recently Recovered From Coronavirus Disease 2019

Satoshi Ide, Hiromasa Hayama, Yusuke Asai, Mari Terada, Hidetoshi Nomoto, Satoshi Kutsuna, Norio Ohmagari, Yukio Hiroi

Author information

Satoshi Ide
Disease Control and Prevention Center, National Center for Global Health and Medicine [Japan]
Emerging and Reemerging Infectious Diseases, Graduate School of Medicine, Tohoku University [Japan]
Hiromasa Hayama
Department of Cardiology, National Center for Global Health and Medicine [Japan]
Yusuke Asai
AMR Clinical Reference Center, National Center for Global Health and Medicine [Japan]
Mari Terada
Disease Control and Prevention Center, National Center for Global Health and Medicine [Japan]
Hidetoshi Nomoto
Disease Control and Prevention Center, National Center for Global Health and Medicine [Japan]
Emerging and Reemerging Infectious Diseases, Graduate School of Medicine, Tohoku University [Japan]
Satoshi Kutsuna
Disease Control and Prevention Center, National Center for Global Health and Medicine [Japan]
Norio Ohmagari
Disease Control and Prevention Center, National Center for Global Health and Medicine [Japan]
Emerging and Reemerging Infectious Diseases, Graduate School of Medicine, Tohoku University [Japan]
Yukio Hiroi
Department of Cardiology, National Center for Global Health and Medicine [Japan]

Keywords: Coronavirus disease 2019 (COVID-19), High-sensitivity troponin T, Myocardial damage

JOURNAL OPEN ACCESS FULL-TEXT HTML

2021 Volume 85 Issue 6 Pages 944-947

DOI https://doi.org/10.1253/circj.CJ-21-0219

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Abstract

Background:Several studies have reported elevated troponin levels in coronavirus disease 2019 (COVID-19) patients, so we investigated myocardial damage by measuring high-sensitivity troponin T (hsTnT) levels and analyzed the relationship with comorbidities.

Methods and Results:Of 209 patients who recently recovered from COVID-19, 65% had an elevated hsTnT level that was higher than levels in patients with acute phase infection despite most patients (79%) having a mild illness. The hsTnT levels correlated with disease severity, sex, comorbidities, and ACEi and ARB use.

Conclusions:Myocardial damage occurs in the recovery phase of COVID-19, and its evaluation, regardless of patient age, should be considered.

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