Restored Cardiac Conditions and Left Ventricular Function After Parathyroidectomy in a Hemodialysis Patient Parathyroidectomy Improves Cardiac Fatty Acid Metabolism Assessed by <sup>123</sup>I-BMIPP

Mamoru Nanasato; Norihiko Goto; Satoshi Isobe; Kazumasa Unno; Haruo Hirayama; Tetsuhiko Sato; Susumu Matsuoka; Takaharu Nagasaka; Yoshihiro Tominaga; Kazuharu Uchida; Toyoaki Murohara

doi:10.1253/circj.CJ-08-0415

This article has now been updated. Please use the final version.

Restored Cardiac Conditions and Left Ventricular Function After Parathyroidectomy in a Hemodialysis Patient

Parathyroidectomy Improves Cardiac Fatty Acid Metabolism Assessed by ¹²³I-BMIPP

Mamoru Nanasato, Norihiko Goto, Satoshi Isobe, Kazumasa Unno, Haruo Hirayama, Tetsuhiko Sato, Susumu Matsuoka, Takaharu Nagasaka, Yoshihiro Tominaga, Kazuharu Uchida, Toyoaki Murohara

Author information

Mamoru Nanasato
Cardiovascular Center, Nagoya Daini Red Cross Hospital
Norihiko Goto
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital
Satoshi Isobe
Department of Cardiology, Kami-iida Dai-ichi General Hospital
Kazumasa Unno
Department of Cardiology, Nagoya University
Haruo Hirayama
Cardiovascular Center, Nagoya Daini Red Cross Hospital
Tetsuhiko Sato
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital
Susumu Matsuoka
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital
Takaharu Nagasaka
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital
Yoshihiro Tominaga
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital
Kazuharu Uchida
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital
Toyoaki Murohara
Department of Cardiology, Nagoya University

Keywords: Hemodialysis, Left ventricular function, Parathyroidectomy, Scintigraphy

JOURNAL FREE ACCESS Advance online publication

Article ID: CJ-08-0415

DOI https://doi.org/10.1253/circj.CJ-08-0415

The final version of this article is now available: Vol. 73 (2009) , No. 10 p.1956

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Abstract

A 62 year-old female hemodialysis patient underwent parathyroidectomy to treat secondary hyperparathyroidism. On the preoperative assessment, the plasma levels of parathyroid hormone (PTH) and B-type natriuretic peptide (BNP) were elevated. Echocardiography showed reduced left ventricular (LV) contraction. Myocardial iodine-123-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid (¹²³I-BMIPP) scintigraphy showed moderately reduced tracer uptake in the postero-inferior area on single-photon emission computed tomography and decreased washout on the planar images. After parathyroidectomy, the plasma levels of PTH and BNP decreased, followed by improvement in LV contraction. Myocardial ¹²³I-BMIPP scintigraphy revealed that the washout on planar images had increased, which suggests that myocardial ¹²³I-BMIPP scintigraphy is useful for estimating the effect of parathyroidectomy on cardiac function.

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