Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Communications to the Editor
Lewis Acid-Promoted Cycloaddition Reaction of Cyclopropanes with Allylsilanes
Yoshiaki SUGITAShiori YAMADOIHiroki HOSOYAIchiro YOKOE
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2001 年 49 巻 5 号 p. 657-658

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The treatment of cyclopropanes having donor and acceptor substituents at the vicinal positions on the cyclopropane ring with a Lewis acid readily generates a 1, 3-zwitterion, which reacted with allylsilanes to produce cycloadducts and allylic products. It was found that the yield of the cycloadduct depends on the steric demand of the alkyl substituents on the silicon atom.
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© 2001 The Pharmaceutical Society of Japan
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