Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Biomimetic Reduction of Nimesulide with NaBH4 Catalyzed by Metalloporphyrins
Shive Murat Singh ChauhanSrinivas Appan KandadaiAnil Kumar
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2002 Volume 50 Issue 10 Pages 1421-1422

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Abstract

The biomimetic reduction of anti-inflammatory drug, nimesulide (1) with sodium borohydride catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides [TAPFe(III)Cl] has been studied in organic solvents under anaerobic and aerobic conditions.

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© 2002 The Pharmaceutical Society of Japan
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