Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Ardisiphenols and Other Antioxidant Principles from the Fruits of Ardisia colorata
Megumi SuminoToshikazu SekineNijsiri RuangrungsiKazuei IgarashiFumio Ikegami
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2002 Volume 50 Issue 11 Pages 1484-1487

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Abstract

Novel alkylphenols, ardisiphenols A—C (1—3) and a novel bergenin derivative, demethoxybergenin (10) were isolated from the fruits of Ardisia colorata (Myrsinaceae), together with known alkylresorcinols (4—6), embelin (7), myricetin (8), quercetin (9), bergenin (11), norbergenin (12), kaempferol (13), quercetin-3-O-β-D-glucopyranoside (14) and gallic acid (15). Their structures were determined by NMR, MS(/MS) analyses and other spectroscopic methods. Ardisiphenols showed moderate scavenging activities toward 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and showed cytotoxicity against the murine breast cancer cell line, FM3A.

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© 2002 The Pharmaceutical Society of Japan
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