Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Pyridazines. Part 31: Synthesis and Antiplatelet Activity of 4,5-Disubstituted-6-phenyl-3(2H)-pyridazinones
Eddy SoteloNuria FraizMatilde YáñezReyes LagunaErnesto CanoEnrique Raviña
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2002 Volume 50 Issue 12 Pages 1574-1577

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Abstract

This paper describes the synthesis and the antiplatelet activity of a series of 4,5-disubstituted-6-phenyl-3(2H)-pyridazinones. Some of these compounds show a dose-dependent activity and were found to be more active than their 5-substituted analogues.

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© 2002 The Pharmaceutical Society of Japan
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