Five New Chromones Possessing Monoamine Oxidase Inhibitory Activity from an Ascomycete, Chaetomium quadrangulatum

Haruhiro Fujimoto; Masato Nozawa; Emi Okuyama; Masami Ishibashi

doi:10.1248/cpb.50.330

Regular Articles

Five New Chromones Possessing Monoamine Oxidase Inhibitory Activity from an Ascomycete, Chaetomium quadrangulatum

Haruhiro Fujimoto, Masato Nozawa, Emi Okuyama, Masami Ishibashi

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Keywords: Chaetomium quadrangulatum, chromone, monoamine oxidase (MAO) inhibitory activity, chaetoquadrin, fungal metabolite, Ascomycete

JOURNAL FREE ACCESS

2002 Volume 50 Issue 3 Pages 330-336

DOI https://doi.org/10.1248/cpb.50.330

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Abstract

Five novel chromones (1,4-benzopyran-4-ones), among which three are tetracyclic and one contains a sulfonyl group, have been isolated from an Ascomycete, Chaetomium quadrangulatum, as monoamine oxidase inhibitory features, and named chaetoquadrins A (1)—E (5).

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