Patavine, a New Arylnaphthalene Lignan Glycoside from Shoot Cultures of Haplophyllum patavinum

Gabbriella Innocenti; Lucia Puricelli; Sonia Piacente; Rosy Caniato; Raffaella Filippini; Elsa Mariella Cappelletti

doi:10.1248/cpb.50.844

Notes

Patavine, a New Arylnaphthalene Lignan Glycoside from Shoot Cultures of Haplophyllum patavinum

Gabbriella Innocenti, Lucia Puricelli, Sonia Piacente, Rosy Caniato, Raffaella Filippini, Elsa Mariella Cappelletti

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Keywords: Haplophyllum, tissue culture, lignan, cytotoxicity

JOURNAL FREE ACCESS

2002 Volume 50 Issue 6 Pages 844-846

DOI https://doi.org/10.1248/cpb.50.844

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Abstract

A new arylnaphthalene lignan glycoside, patavine (1), together with five known lignans, justicidin B (2), diphyllin (3), tuberculatin (4), majidine (5), and arabelline (6) were isolated from shoot cultures of Haplophyllum patavinum. The structure of the new compound was elucidated by extensive one-dimensional (1D) and two-dimensional (2D) NMR experiments and mass spectrometry. The cytotoxicity of compounds 1, and 3—6 against LoVo human colon carcinoma cells was investigated.

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