Synthesis and Biological Activity of Sulfur-Containing Aryl-aldehyde Schiff Bases

Jyh-Jia Jiang; Tsu-Chung Chang; Wen-lin Hsu; Jing-Min Hwang; Ling-Yih Hsu

doi:10.1248/cpb.51.1307

Notes

Synthesis and Biological Activity of Sulfur-Containing Aryl-aldehyde Schiff Bases

Jyh-Jia Jiang, Tsu-Chung Chang, Wen-lin Hsu, Jing-Min Hwang, Ling-Yih Hsu

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Keywords: aryl-aldehyde Schiff base, antioxidant, radioprotection

JOURNAL FREE ACCESS

2003 Volume 51 Issue 11 Pages 1307-1310

DOI https://doi.org/10.1248/cpb.51.1307

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Abstract

A series of chemically modified aryl-aldehyde Schiff bases has been synthesized and tested for their antioxidant activity and radiation protection. We observed that disulfide-containing aryl-aldehyde Schiff base 6c exhibited potent free radical scavenging, antioxidation, and radioprotection activities.

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