Synthesis of Hexahydropyridazine-3-phosphonic Acid

Mamoru Kaname; Kazuo Yoshinaga; Yasushi Arakawa; Shigeyuki Yoshifuji

doi:10.1248/cpb.52.160

Notes

Synthesis of Hexahydropyridazine-3-phosphonic Acid

Mamoru Kaname, Kazuo Yoshinaga, Yasushi Arakawa, Shigeyuki Yoshifuji

著者情報

キーワード: hexahydropyridazine-3-phosphonic acid, phosphonylation, one-pot reaction, piperidazine-3-phosphonic acid, α-hydrazinophosphonic acid, hetero-Diels–Alder reaction

ジャーナルフリー

2004 年 52 巻 1 号 p. 160-162

DOI https://doi.org/10.1248/cpb.52.160

詳細

抄録

The synthesis of hexahydropyridazine-3-phosphonic acid (piperidazine-3-phosphonic acid) was performed via a hetero-Diels–Alder reaction followed by Lewis acid-catalyzed phosphonylation. This two-step procedure was improved to a one-pot reaction.

責任著者(Corresponding author)

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