2004 年 52 巻 10 号 p. 1249-1250
From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1—8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), β-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-β-D-glucopyranoside (9), and limonen-10-ol 10-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (10). Compounds 1 (3.1 μM), 2 (3.1 μM), 3 (3.1 μM), 5 (6.2 μM), 6 (6.2 μM), and 8 (6.2 μM) were effective against epimastigotes of Trypanosoma cruzi.
