Thalidomide as a Nitric Oxide Synthase Inhibitor and Its Structural Development

Rumiko Shimazawa; Hiroko Sano; Aya Tanatani; Hiroyuki Miyachi; Yuichi Hashimoto

doi:10.1248/cpb.52.498

Communications to the Editor

Thalidomide as a Nitric Oxide Synthase Inhibitor and Its Structural Development

Rumiko Shimazawa, Hiroko Sano, Aya Tanatani, Hiroyuki Miyachi, Yuichi Hashimoto

著者情報

キーワード: thalidomide, nitric oxide synthase (NOS), inhibitor, structural development

ジャーナルフリー

2004 年 52 巻 4 号 p. 498-499

DOI https://doi.org/10.1248/cpb.52.498

詳細

抄録

Thalidomide has been found to exhibit weak nitric oxide synthase (NOS)-inhibitory activity. Structural development studies of thalidomide showed that some N-2,6-dimethylphenylhomophthalimide analogs possess NOS-inhibiting activity.

責任著者(Corresponding author)

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