Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Communications to the Editor
Asymmetric Michael Reaction Promoted by New Chiral Phase-Transfer Catalysts
Shigeru AraiKazuyuki TokumaruToyohiko Aoyama
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2004 Volume 52 Issue 5 Pages 646-648

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Abstract

A catalytic asymmetric Michael reaction promoted by new chiral quaternary ammonium salts is described. The products are obtained with moderate ee (up to 75% ee), and the enantioselectivity is strongly dependent on both the substituents on the aromatic rings and the ammonium moiety in the catalysts.

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© 2004 The Pharmaceutical Society of Japan
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