Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Acaricidal Daphnane Diterpenoids from Trigonostemon reidioides (KURZ) CRAIB roots
Noppamas SoonthornchareonnonMonnun SakayarojkulMasahiko IsakaVanna MahakittikunWongsatit ChuakulPrapai Wongsinkongman
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ジャーナル フリー

2005 年 53 巻 2 号 p. 241-243

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抄録
A new daphnane diterpenoid, rediocide F (1), was isolated together with three known compounds, rediocides A (2), C (3) and E (4), from the hexane extract of Trigonostemon reidioides roots by bioassay-guided fractionation for acaricidal activity on Dermatophagoides pteronyssinus, Thai common house dust mite. The structure of rediocide F (1) was established as the demethyl analog of rediocide C (3) on the basis of spectral analysis. Compounds 1—4 exhibited potent activity against D. pteronyssinus with respective LC50 values of 2.53, 0.78, 5.59 and 0.92 μg/cm2.
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© 2005 The Pharmaceutical Society of Japan
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