Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Bioactive Pyranoxanthones from the Roots of Calophyllum blancoi
Ya-Ching ShenLi-Tang WangAshraf Taha KhalilLien Chai ChiangPei-Wen Cheng
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2005 年 53 巻 2 号 p. 244-247

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Phytochemical investigation of the roots of Calophyllum blancoi growing in Taiwan resulted in the isolation of three new pyranoxanthones, blancoxanthone (1), acetyl blancoxanthone (2) and 3-hydroxyblancoxanthone (3), in addition to two known pyranoxanthones, pyranojacaeubin (4) and caloxanthone (5). Structural characterization of the isolated compounds was determined by spectral analyses especially 2-D NMR. Biological study of the isolated xanthones revealed that blancoxanthone (1) exhibited significant anti-coronavirus activity.
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© 2005 The Pharmaceutical Society of Japan
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