First Total Synthesis of Justicidone, a p-Quinone-Lignan Derivative from Justicia hyssopifolia

Abstract

The first synthesis of justicidone (4-(1′,3′-Benzodioxol-5′-yl)-6-methoxynaphtho[2,3-c]furan-1,5,8(3H)-trione) was carried out from piperonal, as a starting compound, through a lineal process using well known reactions.