New Plastoquinones Isolated from the Brown Alga, Sargassum micracanthum

Jun Mori; Makoto Iwashima; Hiroko Wakasugi; Haruo Saito; Takayuki Matsunaga; Masaru Ogasawara; Satoshi Takahashi; Hideyo Suzuki; Toshimitsu Hayashi

doi:10.1248/cpb.53.1159

Regular Articles

New Plastoquinones Isolated from the Brown Alga, Sargassum micracanthum

Jun Mori, Makoto Iwashima, Hiroko Wakasugi, Haruo Saito, Takayuki Matsunaga, Masaru Ogasawara, Satoshi Takahashi, Hideyo Suzuki, Toshimitsu Hayashi

著者情報

キーワード: plastoquinone, antioxidative activity, lipid peroxidation, radical scavenger, cytotoxic activity, Sargassum micracanthum

ジャーナルフリー

2005 年 53 巻 9 号 p. 1159-1163

DOI https://doi.org/10.1248/cpb.53.1159

詳細

抄録

Four new plastoquinones were isolated from the methanolic extract of the brown alga, Sargassum micracanthum. Their structures were elucidated based on spectroscopic analysis and chemical conversions from 2-geranylgeranyl-6-methyl-1,4-benzohydroquinone. These plastoquinones exhibited significant antioxidant activities such as an inhibitory effect on lipid peroxidation and a radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH). Some of the new plastoquiones showed cytotoxic activity against cancer cell line.

責任著者(Corresponding author)

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