Bioactive Saponins and Glycosides. XXVIII. New Triterpene Saponins, Foliatheasaponins I, II, III, IV, and V, from Tencha (the Leaves of Camellia sinensis)

Toshio Morikawa; Seikou Nakamura; Yasuyo Kato; Osamu Muraoka; Hisashi Matsuda; Masayuki Yoshikawa

doi:10.1248/cpb.55.293

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Bioactive Saponins and Glycosides. XXVIII. New Triterpene Saponins, Foliatheasaponins I, II, III, IV, and V, from Tencha (the Leaves of Camellia sinensis)

Toshio Morikawa, Seikou Nakamura, Yasuyo Kato, Osamu Muraoka, Hisashi Matsuda, Masayuki Yoshikawa

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Keywords: Camellia sinensis, Tencha, foliatheasaponin, degranulation inhibitor, triterpene saponin, tea plant

JOURNAL FREE ACCESS

2007 Volume 55 Issue 2 Pages 293-298

DOI https://doi.org/10.1248/cpb.55.293

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Abstract

New triterpene saponins, foliatheasaponins I—V, were isolated from the methanolic extract of Tencha [the leaves of Camellia sinensis (L.) O. KUNTZE (Theaceae)]. The chemical structures of these new saponins were elucidated on the basis of chemical and physicochemical evidence. Among the new saponins, foliatheasaponins II and III, were found to inhibit release of β-hexosaminidase, as a marker of antigen-induced degranulation, in RBL-2H3 cells.

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