Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Six New Triterpenoid Saponins from the Leaves of Ilex oblonga and Their Inhibitory Activities against TMV Replication
Zu-Jian WuMing-An OuyangCong-Zhou WangZheng-Kun Zhang
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2007 年 55 巻 3 号 p. 422-427

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Six new triterpenoid saponins of the ursane types were isolated from the MeOH extract of the leaves of Ilex oblonga. They were oblonganoside A (1), oblonganoside B (2), oblonganoside C (6), oblonganoside D (8), oblonganoside E (9), and oblonganoside F (10), together with three known triterpenoid saponins. The structures of these compounds were elucidated on the basis of spectroscopic analysis, and compound 1 showed appreciable inhibitory activity against TMV replication with EC50 value 0.074 mM.
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© 2007 The Pharmaceutical Society of Japan
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