Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
A New Pyrone Derivative from the Endophytic Fungus Penicillium paxilli PSU-A71
Vatcharin RukachaisirikulJuthanat KaeobamrungWannarat PanwiriyaratPimchanok SaitaiYaowapa SukpondmaSouwalak PhongpaichitJariya Sakayaroj
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2007 Volume 55 Issue 9 Pages 1383-1384

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Abstract

One new pyrone derivative, named penicillone (1), together with paxilline, pyrenocines A (2) and B (3) were isolated from the endophytic fungus Penicillium paxilli PSU-A71. The structures were elucidated by spectroscopic methods. Pyrenocine B (3) mildly inhibited the growth of Microsporum gypseum SH-MU-4 with a MIC value of 32 μg/ml.

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© 2007 The Pharmaceutical Society of Japan
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