Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Flavonoids from the Heartwood of Dalbergia odorifera and Their Protective Effect on Glutamate-Induced Oxidative Injury in HT22 Cells
Ren-Bo AnGil-Saeng JeongYoun-Chul Kim
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2008 年 56 巻 12 号 p. 1722-1724

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Two flavonoids, 4,2′,5′-trihydroxy-4′-methoxychalcone (1) and (2S)-6,7,4′-trihydroxyflavan (2), along with fourteen known flavonoids and two other known arylbenzofurans were isolated from the heartwood of Dalbergia odorifera. The structure of compounds 1 and 2 were established by spectroscopic (NMR and MS) analyses. Of the isolates, eight compounds (1, 4, 7, 10, 12, 14, 15, 17) were found to have potent protective effect on glutamate-induced oxidative injury in HT22 cells.

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© 2008 The Pharmaceutical Society of Japan
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