The Enantioselective Total Synthesis of a β-Carboline Alkaloid, (S)-(−)-Dichotomine C

抄録

The first enantioselective synthesis of a β-carboline alkaloid, dichotomine C, possessing antiallergic effects, was achieved by constructing a β-carboline framework based on the microwave-assisted thermal electrocyclic reaction of a 1-azahexatriene system, followed by the Sharpless asymmetric dihydroxylation.