Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
One-Pot Synthesis of Simple Alkaloids: 2,3-Polymethylene-4(3H)-quinazolinones, Luotonin A, Tryptanthrin, and Rutaecarpine
Katherine Chae JahngSeung Ill KimDong Hyeon KimChang Seob SeoJong-Keun SonSeung Ho LeeEung Seok LeeYurngdong Jahng
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2008 年 56 巻 4 号 p. 607-609

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One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl2 is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.
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© 2008 The Pharmaceutical Society of Japan
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